Pesquisa | BVS Integralidade em Saúde

1.

Trial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis.

Richeldi, Luca; Azuma, Arata; Cottin, Vincent; Hesslinger, Christian; Stowasser, Susanne; Valenzuela, Claudia; Wijsenbeek, Marlies S; Zoz, Donald F; Voss, Florian; Maher, Toby M.

N Engl J Med ; 386(23): 2178-2187, 2022 06 09.

Artigo em Inglês | MEDLINE | ID: mdl-35569036

2.

Deep Learning-based Segmentation of CT Scans Predicts Disease Progression and Mortality in IPF.

Thillai, Muhunthan; Oldham, Justin M; Ruggiero, Alessandro; Kanavati, Fahdi; McLellan, Tom; Saini, Gauri; Johnson, Simon R; Ble, Francois-Xavier; Azim, Adnan; Ostridge, Kristoffer; Platt, Adam; Belvisi, Maria; Maher, Toby M; Molyneaux, Philip L.

Am J Respir Crit Care Med ; 2024 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-38452227

3.

Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine.

Adegunsoye, Ayodeji; Kropski, Jonathan A; Behr, Juergen; Blackwell, Timothy S; Corte, Tamera J; Cottin, Vincent; Glanville, Allan; Glassberg, Marilyn K; Griese, Matthias; Hunninghake, Gary M; Johannson, Kerri A; Keane, Michael P; Kim, John S; Kolb, Martin; Maher, Toby M; Oldham, Justin M; Podolanczuk, Anna J; Rosas, Ivan O; Martinez, Fernando J; Noth, Imre; Schwartz, David A.

Am J Respir Crit Care Med ; 2024 Apr 04.

Artigo em Inglês | MEDLINE | ID: mdl-38573068

4.

Phase 2, Double-Blind, Placebo-controlled Trial of a c-Jun N-Terminal Kinase Inhibitor in Idiopathic Pulmonary Fibrosis.

Mattos, Waldo L L D; Khalil, Nasreen; Spencer, Lisa G; Bonella, Francesco; Folz, Rodney J; Rolf, J Douglass; Mogulkoc, Nesrin; Lancaster, Lisa H; Jenkins, R Gisli; Lynch, David A; Noble, Paul W; Maher, Toby M; Cottin, Vincent; Senger, Stefanie; Horan, Gerald S; Greenberg, Steven; Popmihajlov, Zoran.

Am J Respir Crit Care Med ; 2024 Mar 14.

Artigo em Inglês | MEDLINE | ID: mdl-38484130

5.

Machine Learning of Plasma Proteomics Classifies Diagnosis of Interstitial Lung Disease.

Huang, Yong; Ma, Shwu-Fan; Oldham, Justin M; Adegunsoye, Ayodeji; Zhu, Daisy; Murray, Susan; Kim, John S; Bonham, Catherine; Strickland, Emma; Linderholm, Angela L; Lee, Cathryn T; Paul, Tessy; Mannem, Hannah; Maher, Toby M; Molyneaux, Philip L; Strek, Mary E; Martinez, Fernando J; Noth, Imre.

Am J Respir Crit Care Med ; 2024 Feb 29.

Artigo em Inglês | MEDLINE | ID: mdl-38422478

6.

Pulmonary Fibrosis Stakeholder Summit: A Joint NHLBI, Three Lakes Foundation, and Pulmonary Fibrosis Foundation Workshop Report.

Montesi, Sydney B; Gomez, Christian R; Beers, Michael; Brown, Robert; Chattopadhyay, Ishanu; Flaherty, Kevin R; Garcia, Christine Kim; Gomperts, Brigitte; Hariri, Lida P; Hogaboam, Cory M; Jenkins, R Gisli; Kaminski, Naftali; Kim, Grace Hyun J; Königshoff, Melanie; Kolb, Martin; Kotton, Darrell N; Kropski, Jonathan A; Lasky, Joseph; Magin, Chelsea M; Maher, Toby M; McCormick, Mark; Moore, Bethany B; Nickerson-Nutter, Cheryl; Oldham, Justin; Podolanczuk, Anna J; Raghu, Ganesh; Rosas, Ivan; Rowe, Steven M; Schmidt, William T; Schwartz, David; Shore, Jessica E; Spino, Cathie; Craig, J Matthew; Martinez, Fernando J.

Am J Respir Crit Care Med ; 209(4): 362-373, 2024 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-38113442

7.

Meaningful Endpoints for Idiopathic Pulmonary Fibrosis (IPF) Clinical Trials: Emphasis on 'Feels, Functions, Survives'. Report of a Collaborative Discussion in a Symposium with Direct Engagement from Representatives of Patients, Investigators, the National Institutes of Health, a Patient Advocacy Organization, and a Regulatory Agency.

Raghu, Ganesh; Ghazipura, Marya; Fleming, Thomas R; Aronson, Kerri I; Behr, Jürgen; Brown, Kevin K; Flaherty, Kevin R; Kazerooni, Ella A; Maher, Toby M; Richeldi, Luca; Lasky, Joseph A; Swigris, Jeffrey J; Busch, Robert; Garrard, Lili; Ahn, Dong-Hyun; Li, Ji; Puthawala, Khalid; Rodal, Gabriela; Seymour, Sally; Weir, Nargues; Danoff, Sonye K; Ettinger, Neil; Goldin, Jonathan; Glassberg, Marilyn K; Kawano-Dourado, Leticia; Khalil, Nasreen; Lancaster, Lisa; Lynch, David A; Mageto, Yolanda; Noth, Imre; Shore, Jessica E; Wijsenbeek, Marlies; Brown, Robert; Grogan, Daniel; Ivey, Dorothy; Golinska, Patrycja; Karimi-Shah, Banu; Martinez, Fernando J.

Am J Respir Crit Care Med ; 209(6): 647-669, 2024 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-38174955

8.

Effects of nintedanib on symptoms in patients with progressive pulmonary fibrosis.

Wijsenbeek, Marlies; Swigris, Jeffrey J; Inoue, Yoshikazu; Kreuter, Michael; Maher, Toby M; Suda, Takafumi; Baldwin, Michael; Mueller, Heiko; Rohr, Klaus B; Flaherty, Kevin R.

Eur Respir J ; 63(2)2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38135442

9.

Combination of BAL and Computed Tomography Differentiates Progressive and Non-progressive Fibrotic Lung Diseases.

Barnett, Joseph L; Maher, Toby M; Quint, Jennifer K; Adamson, Alex; Wu, Zhe; Smith, David J F; Rawal, Bhavin; Nair, Arjun; Walsh, Simon L F; Desai, Sujal R; George, Peter M; Kokosi, Maria; Jenkins, Gisli; Kouranos, Vasilis; Renzoni, Elisabetta A; Rice, Alex; Nicholson, Andrew G; Chua, Felix; Wells, Athol U; Molyneaux, Philip L; Devaraj, Anand.

Am J Respir Crit Care Med ; 208(9): 975-982, 2023 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-37672028

10.

Idiopathic Pulmonary Fibrosis Is Associated with Common Genetic Variants and Limited Rare Variants.

Peljto, Anna L; Blumhagen, Rachel Z; Walts, Avram D; Cardwell, Jonathan; Powers, Julia; Corte, Tamera J; Dickinson, Joanne L; Glaspole, Ian; Moodley, Yuben P; Vasakova, Martina Koziar; Bendstrup, Elisabeth; Davidsen, Jesper R; Borie, Raphael; Crestani, Bruno; Dieude, Philippe; Bonella, Francesco; Costabel, Ulrich; Gudmundsson, Gunnar; Donnelly, Seamas C; Egan, Jim; Henry, Michael T; Keane, Michael P; Kennedy, Marcus P; McCarthy, Cormac; McElroy, Aoife N; Olaniyi, Joshua A; O'Reilly, Katherine M A; Richeldi, Luca; Leone, Paolo M; Poletti, Venerino; Puppo, Francesco; Tomassetti, Sara; Luzzi, Valentina; Kokturk, Nurdan; Mogulkoc, Nesrin; Fiddler, Christine A; Hirani, Nikhil; Jenkins, R Gisli; Maher, Toby M; Molyneaux, Philip L; Parfrey, Helen; Braybrooke, Rebecca; Blackwell, Timothy S; Jackson, Peter D; Nathan, Steven D; Porteous, Mary K; Brown, Kevin K; Christie, Jason D; Collard, Harold R; Eickelberg, Oliver.

Am J Respir Crit Care Med ; 207(9): 1194-1202, 2023 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-36602845

11.

PCSK6 and Survival in Idiopathic Pulmonary Fibrosis.

Oldham, Justin M; Allen, Richard J; Lorenzo-Salazar, Jose M; Molyneaux, Philip L; Ma, Shwu-Fan; Joseph, Chitra; Kim, John S; Guillen-Guio, Beatriz; Hernández-Beeftink, Tamara; Kropski, Jonathan A; Huang, Yong; Lee, Cathryn T; Adegunsoye, Ayodeji; Pugashetti, Janelle Vu; Linderholm, Angela L; Vo, Vivian; Strek, Mary E; Jou, Jonathan; Muñoz-Barrera, Adrian; Rubio-Rodriguez, Luis A; Hubbard, Richard; Hirani, Nik; Whyte, Moira K B; Hart, Simon; Nicholson, Andrew G; Lancaster, Lisa; Parfrey, Helen; Rassl, Doris; Wallace, William; Valenzi, Eleanor; Zhang, Yingze; Mychaleckyj, Josyf; Stockwell, Amy; Kaminski, Naftali; Wolters, Paul J; Molina-Molina, Maria; Banovich, Nicholas E; Fahy, William A; Martinez, Fernando J; Hall, Ian P; Tobin, Martin D; Maher, Toby M; Blackwell, Timothy S; Yaspan, Brian L; Jenkins, R Gisli; Flores, Carlos; Wain, Louise V; Noth, Imre.

Am J Respir Crit Care Med ; 207(11): 1515-1524, 2023 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-36780644

12.

Interstitial Lung Disease: A Review.

Maher, Toby M.

JAMA ; 2024 Apr 22.

Artigo em Inglês | MEDLINE | ID: mdl-38648021

13.

Interstitial lung diseases.

Wijsenbeek, Marlies; Suzuki, Atsushi; Maher, Toby M.

Lancet ; 400(10354): 769-786, 2022 09 03.

Artigo em Inglês | MEDLINE | ID: mdl-35964592

14.

Cluster analysis of transcriptomic datasets to identify endotypes of idiopathic pulmonary fibrosis.

Kraven, Luke M; Taylor, Adam R; Molyneaux, Philip L; Maher, Toby M; McDonough, John E; Mura, Marco; Yang, Ivana V; Schwartz, David A; Huang, Yong; Noth, Imre; Ma, Shwu Fan; Yeo, Astrid J; Fahy, William A; Jenkins, R Gisli; Wain, Louise V.

Thorax ; 78(6): 551-558, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-35534152

15.

The causal relationship between gastro-oesophageal reflux disease and idiopathic pulmonary fibrosis: a bidirectional two-sample Mendelian randomisation study.

Reynolds, Carl J; Del Greco M, Fabiola; Allen, Richard J; Flores, Carlos; Jenkins, R Gisli; Maher, Toby M; Molyneaux, Philip L; Noth, Imre; Oldham, Justin M; Wain, Louise V; An, Jiyuan; Ong, Jue-Sheng; MacGregor, Stuart; Yates, Tom A; Cullinan, Paul; Minelli, Cosetta.

Eur Respir J ; 61(5)2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37080571

16.

GLPG1205 for idiopathic pulmonary fibrosis: a phase 2 randomised placebo-controlled trial.

Strambu, Irina R; Seemayer, Christian A; Fagard, Liesbeth M-C A; Ford, Paul A; Van der Aa, Tom A K; de Haas-Amatsaleh, Angela A; Modgill, Vikas; Santermans, Eva; Sondag, Eric N; Helmer, Eric G; Maher, Toby M; Costabel, Ulrich; Cottin, Vincent.

Eur Respir J ; 61(3)2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36328358

17.

Extent of fibrosis and lung function decline in patients with systemic sclerosis and interstitial lung disease: data from the SENSCIS trial.

Denton, Christopher P; Goh, Nicole S; Humphries, Stephen M; Maher, Toby M; Spiera, Robert; Devaraj, Anand; Ho, Lawrence; Stock, Christian; Erhardt, Elvira; Alves, Margarida; Wells, Athol U.

Rheumatology (Oxford) ; 62(5): 1870-1876, 2023 05 02.

Artigo em Inglês | MEDLINE | ID: mdl-36111858

18.

Impact of lung function and baseline clinical characteristics on patient-reported outcome measures in systemic sclerosis-associated interstitial lung disease.

Kreuter, Michael; Hoffmann-Vold, Anna-Maria; Matucci-Cerinic, Marco; Saketkoo, Lesley Ann; Highland, Kristin B; Wilson, Hilary; Alves, Margarida; Erhardt, Elvira; Schoof, Nils; Maher, Toby M.

Rheumatology (Oxford) ; 62(SI): SI43-SI53, 2023 02 06.

Artigo em Inglês | MEDLINE | ID: mdl-35640959

19.

Weight loss and outcomes in subjects with progressive pulmonary fibrosis: data from the INBUILD trial.

Kreuter, Michael; Bendstrup, Elisabeth; Jouneau, Stéphane; Maher, Toby M; Inoue, Yoshikazu; Miede, Corinna; Lievens, Dirk; Crestani, Bruno.

Respir Res ; 24(1): 71, 2023 Mar 09.

Artigo em Inglês | MEDLINE | ID: mdl-36894966

20.

Decline in forced vital capacity as a surrogate for mortality in patients with pulmonary fibrosis.

Maher, Toby M; Stowasser, Susanne; Voss, Florian; Bendstrup, Elisabeth; Kreuter, Michael; Martinez, Fernando J; Sime, Patricia J; Stock, Christian.

Respirology ; 28(12): 1147-1153, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-37646126

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